twain32.dll should not be in the c:WindowsSysWoW64, it should only be in c:Windows
There was an issue with an older version of the TWAIN 2.0 DSM that could not handle this issue, but it has been resolved.
Make sure you are using the latest version of the TWAIN2 DSM.
Can you post a TWAIN2 DSM log file?
http://www.twainforum.org/viewtopic.php?p=7695
Regards,
Jim Watters
**************************************************
JFL Peripheral Solutions Inc.
http://www.jflinc.com/
Your Expert Source of Custom Software and Services
for TWAIN Applications, Data Sources,
Peripheral Drivers and Support Software.
**************************************************